2024-03-29T12:49:50Zhttp://uvadoc.uva.es/oai/requestoai:uvadoc.uva.es:10324/217242021-06-24T07:42:10Zcom_10324_1186com_10324_931com_10324_894com_10324_28542com_10324_952col_10324_1404col_10324_28543
Pozo, Juan del
Casares González, Juan Ángel
Espinet Rubio, Pablo
2016
Producción Científica
A bimetallic system Pd/CuF2, catalytic in Pd and stoichiometric in Cu, is very efficient and selective for the coupling of fairly hindered aryl silanes with aryl, anisyl, phenylaldehide, or pyridyl iodides of conventional size. The reaction involves the activation of the silane by CuII followed by disproportionation and
transmetalation from the CuI(aryl) to PdII, on which coupling takes place. The CuIII formed in the disproportionation is reduced to CuI(aryl) by the aryl silane in excess, so that the CuF2 used is fully converted into CuI(aryl) and used in the coupling. Moreover, no extra source of fluoride is needed. Interesting size selectivity towards coupling is found in competitive reactions of hindered aryl silanes. Easily accessible [PdCl2(IDM)(AsPh3)] is by far the best catalyst, and the isolated products are esentially free of As or Pd (< 1 ppm). The mechanistic aspects of the process are experimentally examined and discussed.
application/pdf
http://uvadoc.uva.es/handle/10324/21724
eng
Wiley
Catalyst
In Situ Generation of ArCu from CuF2 Makes Coupling of Bulky Aryl Silanes Feasible and Highly Efficient
info:eu-repo/semantics/article
TEXT
UVaDOC. Repositorio Documental de la Universidad de Valladolid
Hispana