2024-03-28T13:22:51Zhttp://uvadoc.uva.es/oai/requestoai:uvadoc.uva.es:10324/291522021-06-24T07:32:02Zcom_10324_28708com_10324_954com_10324_894col_10324_28709
Álvarez González, Celedonio Manuel
García Rodríguez, Raúl
Miguel San José, Daniel
2018-03-19T12:23:42Z
2018-03-19T12:23:42Z
2016
Dalton Transactions 2016, 45 , pp. 963 – 972
1477-9226
http://uvadoc.uva.es/handle/10324/29152
10.1039/C5DT01256B
Metallamacrocycles of 12, 16, and 22 members are obtained by deprotonation of the carboxylic group of the side chain of iminopyridine complexes derived from the amino acid β-alanine, and the peptides Gly–Gly and Gly–Gly–Gly. Instead of the expected intramolecular attack to give tridentate (N,N,O) ligands, the deprotonated carboxylate attacks in an inter-molecular manner to give dimers in which the ligand acts as a bridge bonded in a κ2(N,N′) chelating fashion to one metal and as κ(O) to the other metal. The formation of the dimers is supported by NMR spectroscopy, mass spectrometry and X-ray crystallography.
eng
info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by-nc-nd/4.0/
Attribution-NonCommercial-NoDerivatives 4.0 International
Metallamacrocycle formation through dimerization of metal bioconjugates derived from amino acids and peptides
info:eu-repo/semantics/article