2024-03-29T05:12:10Zhttp://uvadoc.uva.es/oai/requestoai:uvadoc.uva.es:10324/214502021-06-24T07:42:22Zcom_10324_1187com_10324_931com_10324_894com_10324_28542com_10324_952col_10324_1408col_10324_28543
7-Endo selenocyclization reactions on chiral 3-prenyl and 3-cinnamyl-2 hydroxymethylperhydro-1,3-benzoxazine derivatives. A way to enantiopure 1,4-oxazepanes
Nieto Román, Francisco Javier
Andrés Juan, Celia
Pérez Encabo, Alfonso
Química orgánica
Enantiopure 1,4-oxazepanes derivatives have been prepared by selenocyclofunctionalization of chiral 3-prenyl- and 3-cinnamyl-2-hydroxymethyl-substituted perhydro-1,3-benzoxazine derivatives. The 7-endo-cyclization occurs in high yields and diastereoselection. The regio and stereochemistry of the cyclization products was dependent of the substitution pattern of the double bond, the nature of the hydroxyl group and the experimental conditions.
2016-12-05T13:18:01Z
2016-12-05T13:18:01Z
2016-12-05T13:18:01Z
2015
info:eu-repo/semantics/article
Organic & Biomolecular Chemistry, 2015,13, p. 9118-9126
1477-0520
http://uvadoc.uva.es/handle/10324/21450
10.1039/C5OB01297J
9118
13
9126
Organic & Biomolecular Chemistry
eng
http://pubs.rsc.org/
info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by-nc-nd/4.0/
Attribution-NonCommercial-NoDerivatives 4.0 International
Royal Society of Chemistry