2024-03-29T14:02:59Zhttp://uvadoc.uva.es/oai/requestoai:uvadoc.uva.es:10324/77502021-06-23T09:48:48Zcom_10324_1133com_10324_931com_10324_894col_10324_1209
Embryonic cerebrospinal fluid in brain development: neural progenitor control
Gato Casado, Ángel Luis
Alonso Revuelta, María Isabel
Martín, Cristina
Carnicero Gila, Estela María
Moro Balbás, José Antonio
Fernández Gómez, José María Fidel
Lamus Molina, José Francisco
Desmond, Mary E.
Nervioso central, Sistema
Producción Científica
Due to the effort of several research teams across the
world, today we have a solid base of knowledge on the
liquid contained in the brain cavities, its composition, and
biological roles. Although the cerebrospinal fluid (CSF) is
among the most relevant parts of the central nervous system
from the physiological point of view, it seems that it
is not a permanent and stable entity because its composition
and biological properties evolve across life. So, we can
talk about different CSFs during the vertebrate life span.
In this review, we focus on the CSF in an interesting period,
early in vertebrate development before the formation
of the choroid plexus. This specific entity is called “embryonic
CSF.” Based on the structure of the compartment,
CSF composition, origin and circulation, and its interaction
with neuroepithelial precursor cells (the target cells)
we can conclude that embryonic CSF is different from the
CSF in later developmental stages and from the adult CSF.
This article presents arguments that support the singularity
of the embryonic CSF, mainly focusing on its influence
on neural precursor behavior during development and in
adult life.
2014-12-18T13:01:57Z
2014-12-18T13:01:57Z
2014
info:eu-repo/semantics/article
Croat Medical J. Agosto 2014, 55(4) 299-305
0353-9504
http://uvadoc.uva.es/handle/10324/7750
10.3325/cmj.2014.55.299
299
55
305
Croat Med J.
4
eng
info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by-nc-nd/4.0/
Attribution-NonCommercial-NoDerivatives 4.0 International
Karger
SI