RT info:eu-repo/semantics/article
T1 Predicting cardiac surgery–associated acute kidney injury: The CRATE score
A1 Jorge Monjas, Pablo
A1 Bustamante Munguira, Juan
A1 Lorenzo López, Mario
A1 Heredia Rodríguez, María
A1 Fierro Lorenzo, María Inmaculada
A1 Gómez Sánchez, Esther
A1 Hernández, Alfonso
A1 Álvarez González, Francisco Javier
A1 Bermejo Martín, Jesús Francisco
A1 Gómez Pesquera, Estefanía
A1 Gómez Herreras, José Ignacio
A1 Tamayo Gómez, Eduardo
K1 Cardiovascular, Aparato - Cirugía - Complicaciones y secuelas
K1 Enfermedad renal
AB Purpose: Acute kidney injury (AKI) is a frequent complication after cardiac surgery and is associated withincreased mortality. The aim was to design a nondialytic AKI score in patients with previously normal renalfunction undergoing cardiac surgery.Methods: Data were collected on 909 patients who underwent cardiac surgery with cardiopulmonary bypass between2012 and 2014. A total of 810 patients fulfilled the inclusion criteria. Patients were classified as having AKIbased on the RIFLE criteria. Postoperative AKI occurred in 137 patients (16.9%). Several parameters were recordedpreoperatively, intraoperatively, and at intensive care unit admission, looking for a univariate andmultivariate associationwithAKI risk. A second data set of 741 patients, from2 different hospitals,was recorded as a validation cohort.Results: Four independent risk factors were included in the CRATE score: creatinine (odds ratio [OR], 9.66; 95% confidenceinterval [CI], 4.77-19.56; P b .001), EuroSCORE (OR, 1.40; CI, 1.29-1.52; P b .001), lactate (OR, 1.03; CI, 1.01-1.04; P b .001), and cardiopulmonary bypass time (OR, 1.01; CI, 1.01-1.02; P b .001). The accuracy of the model wasgood, with an area under the curve of 0.89 (CI, 0.85-0.92). The CRATE score retained good discrimination in validationcohort, with an area under the curve of 0.81 (95% CI, 0.78-0.85).Conclusions: CRATE score is an accurate and easy to calculate risk score that uses affordable andwidely available variablesin the routine care surgical patients.
PB Elsevier
SN 0883-9441
YR 2015
FD 2015
LK http://uvadoc.uva.es/handle/10324/15241
UL http://uvadoc.uva.es/handle/10324/15241
LA eng
NO Journal of Critical Care, 2016, 31 (1): 130–138
NO Producción Científica
DS UVaDOC
RD 08-may-2024