RT info:eu-repo/semantics/article
T1 Clinical and Molecular Inflammatory Response in Sjögren Syndrome–Associated Dry Eye Patients Under Desiccating Stress
A1 López Miguel, Alberto
A1 Tesón Yudego, María Luisa
A1 Martín Montañez, Vicente
A1 Enriquez De Salamanca Aladro, Amalia
A1 Sternd, Michael E.
A1 Calonge, Margarita
A1 González García, María Jesús
K1 Ojo seco
K1 Sjogren, Síndrome de
AB To evaluate the response of the lacrimal function unit in Sjogren syndrome (SS)-associated dry eye patients exposed to 2 simulated daily life environ-mental conditions.Fourteen female SS dry eye patients were exposed for 2 hours to a controlled normal condition (23 C, 45% relative humidity, and air flow 0.10 m/s) and a controlled adverse condition that simulates desic- cating stress (23 C, 5% relative humidity, and air flow 0.10 m/s). The following dry eye tests were performed before and after the exposure: tear osmolarity, phenol red thread test, conjunctival hyperemia, fluorescein tear break-up time, corneal fluorescein staining, conjunctival lissamine green staining, and Schirmer test. Levels of 16 molecules were analyzed in tears by multiplex immu- nobead analysis.
PB Elsevier Masson
YR 2016
FD 2016
LK http://uvadoc.uva.es/handle/10324/21511
UL http://uvadoc.uva.es/handle/10324/21511
LA eng
NO American Journal of Ophthalmology, 2016, Vol.161, p.133–141 e2
NO Producción Científica
DS UVaDOC
RD 02-may-2024