RT info:eu-repo/semantics/article
T1 Biodegradable Chitosan-Derived Thioureas as Recoverable Supported Organocatalysts – Application to the Stereoselective Aza-Henry Reaction
A1 Andrés García, José María
A1 González Pérez, Fernando
A1 Maestro Fernández, Alicia
A1 Pedrosa Sáez, Rafael
A1 Valle Álvarez, María
K1 Catálisis
K1 Química orgánica
AB Eight different biodegradable chitosan-supported bifunctional chiral thioureas have been prepared as a greener and more sustainable alternative to those supported on petrochemical-derived polymers. These organocatalysts promoted an enantioselective aza-Henry reaction, which afforded good product yields with moderate to high enantioselectivity. The activity and stereodirecting ability of these materials were dependent on the accessibility of the reactants to the active site and increased with the length of the tether that connected the thiourea to the biopolymer. The best performing catalyst was able to be recovered and recycled five times without a loss of activity.
PB Wiley
YR 2017
FD 2017
LK http://uvadoc.uva.es/handle/10324/28949
UL http://uvadoc.uva.es/handle/10324/28949
LA eng
NO European Journal of Organic Chemistry, 2017, Volume 2017, Issue 25, Pages 3658–3665
NO Producción Científica
DS UVaDOC
RD 26-abr-2024