RT info:eu-repo/semantics/article
T1 Metallamacrocycle formation through dimerization of metal bioconjugates derived from amino acids and peptides
A1 Álvarez González, Celedonio Manuel
A1 García Rodríguez, Raúl
A1 Miguel San José, Daniel
K1 Metallamacrocycle
AB Metallamacrocycles of 12, 16, and 22 members are obtained by deprotonation of the carboxylic group of the side chain of iminopyridine complexes derived from the amino acid β-alanine, and the peptides Gly–Gly and Gly–Gly–Gly. Instead of the expected intramolecular attack to give tridentate (N,N,O) ligands, the deprotonated carboxylate attacks in an inter-molecular manner to give dimers in which the ligand acts as a bridge bonded in a κ2(N,N′) chelating fashion to one metal and as κ(O) to the other metal. The formation of the dimers is supported by NMR spectroscopy, mass spectrometry and X-ray crystallography.
PB Royal Society of Chemistry
SN 1477-9226
YR 2016
FD 2016
LK http://uvadoc.uva.es/handle/10324/29152
UL http://uvadoc.uva.es/handle/10324/29152
LA eng
NO Dalton Transactions 2016, 45 , pp. 963 – 972
NO Producción Científica
DS UVaDOC
RD 26-abr-2024