RT info:eu-repo/semantics/article T1 Impact of optimal timing of intake of multi-ingredient performance supplements on sports performance, muscular damage, and hormonal behavior across a ten-week training camp in elite cyclists: A randomized clinical trial A1 Fernández Lázaro, Diego A1 Mielgo Ayuso, Juan Francisco A1 Valle Soto, Miguel del A1 Adams, David P. A1 Gutiérrez Abejón, Eduardo A1 Seco Calvo, Jesús K1 Nutrición K1 Deporte K1 Supplementation K1 Amino acids K1 Muscle recovery K1 Sport performance K1 Suplementación K1 Aminoácidos K1 Recuperación muscular K1 Rendimiento deportivo K1 2407 Biología Celular K1 3206.08 Nutrientes AB Multi-ingredient performance supplements (MIPS), ingested pre- or post-workout, have been shown to increase physiological level effects and integrated metabolic response on exercise. The purpose of this study was to determine the efficacy of pre-and post-training supplementation with its own MIPS, associated with CHO (1 g·kg−1) plus protein (0.3 g·kg−1) on exercise-related benchmarks across a training camp for elite cyclists. Thirty elite male cyclists participated in a randomized non-placebo-controlled trial for ten weeks assigned to one of three groups (n = 10 each): a control group treated with CHO plus protein after training (CG); a group treated with MIPS before training and a CHO plus protein after training, (PRE-MIPS); a group treated with CHO plus protein plus MIPS after training, (POST-MIPS). Performance parameters included (VO2max, peak; median and minimum power (W) and fatigue index (%)); hormonal response (Cortisol; Testosterone; and Testosterone/Cortisol ratio); and muscle biomarkers (Creatine kinase (CK), Lactate dehydrogenase (LDH), and Myoglobin (Mb)) were assessed. MIPS administered before or after training (p ≤ 0.05) was significantly influential in attenuating CK, LDH, and MB; stimulating T response and modulating C; and improved on all markers of exercise performance. These responses were greater when MIPS was administered post-workout. PB MDPI YR 2021 FD 2021 LK https://uvadoc.uva.es/handle/10324/59466 UL https://uvadoc.uva.es/handle/10324/59466 LA eng NO Nutrients, 2021, vol. 13, n. 11, 3746 NO Producción Científica DS UVaDOC RD 21-may-2024