RT info:eu-repo/semantics/article
T1 New insights on the integrated management of plant diseases by RNA strategies: Mycoviruses and RNA interference
A1 Bocos Asenjo, Irene Teresa
A1 Niño Sánchez, Jonathan
A1 Ginésy, Mireille
A1 Díez Casero, Julio Javier
K1 Plant diseases
K1 Enfermedades de las plantas
K1 Plants, Protection of
K1 Plantas - Protección
K1 Hongos - Enfermedades y plagas
K1 Fungal diseases of plants
K1 Phytopathologie
K1 RNA
K1 ARN
K1 Plant genetics
K1 Genética vegetal
K1 Gene silencing
K1 5102.01 Agricultura
K1 3108 Fitopatología
AB RNA-based strategies for plant disease management offer an attractive alternative to agrochemicals that negatively impact human and ecosystem health and lead to pathogen resistance. There has been recent interest in using mycoviruses for fungal disease control after it was discovered that some cause hypovirulence in fungal pathogens, which refers to a decline in the ability of a pathogen to cause disease. Cryphonectria parasitica, the causal agent of chestnut blight, has set an ideal model of management through the release of hypovirulent strains. However, mycovirus-based management of plant diseases is still restricted by limited approaches to search for viruses causing hypovirulence and the lack of protocols allowing effective and systemic virus infection in pathogens. RNA interference (RNAi), the eukaryotic cell system that recognizes RNA sequences and specifically degrades them, represents a promising. RNA-based disease management method. The natural occurrence of cross-kingdom RNAi provides a basis for host-induced gene silencing, while the ability of most pathogens to uptake exogenous small RNAs enables the use of spray-induced gene silencing techniques. This review describes the mechanisms behind and the potential of two RNA-based strategies, mycoviruses and RNAi, for plant disease management. Successful applications are discussed, as well as the research gaps and limitations that remain to be addressed.
PB MDPI
SN 1422-0067
YR 2022
FD 2022
LK https://uvadoc.uva.es/handle/10324/61076
UL https://uvadoc.uva.es/handle/10324/61076
LA eng
NO International Journal of Molecular Sciences, 2022, Vol. 23, Nº. 16,  9236
NO Producción Científica
DS UVaDOC
RD 10-may-2024