RT info:eu-repo/semantics/article T1 Clinical and pathological effects of different acrylic intracorneal ring segments in corneal additive surgery A1 Pérez Merino, Pablo A1 Parra Ruiz, Francisco Javier A1 Ibares Frías, Lucía A1 Gallego Muñoz, Patricia A1 Vázquez Lasa, Blanca A1 Benito Garzón, Lorena A1 San Román Calvar, José Alberto A1 Martínez García, María del Carmen A1 Merayo Lloves, Jesús K1 Cornea - Cirugía AB The objective of this work was to evaluate the potential use of less stiff materials based on acrylic copolymersof methyl methacrylate/2-ethylhexyl acrylate (MMA/EHA) as devices to correct, stabilize andimprove the effect of poly(methyl methacrylate) (PMMA) intracorneal ring segments. MMA/EHA andPMMA intracorneal ring segments were surgically implanted in the corneas of Lohmann Classic hens.The effects of the intracorneal ring segments were assessed by optical measurements and corneal tolerancewas evaluated through biomicroscopic examination over a 90-day observation period and by conventionalhistology. The experimental results demonstrated that the intracorneal ring segments madeof MMA/EHA copolymers provided a significant change in the corneal curvature and an improvedin vivo response compared to those obtained for PMMA rings, which was attributed to the higher flexibilityof the copolymeric materials, indicating that these systems might be considered suitable as analternative to those currently used, for application in clinical practice. PB Elsevier SN 1742-7061 YR 2010 FD 2010 LK http://uvadoc.uva.es/handle/10324/6285 UL http://uvadoc.uva.es/handle/10324/6285 LA eng NO Acta Biomaterialia, 2010, vol. 6, p. 2572-2579 NO Producción Científica DS UVaDOC RD 25-abr-2024