RT info:eu-repo/semantics/article T1 Reciprocal modulation of tyrosine hydroxylasea activity in rat carotid body A1 González, Constancio A1 Kwok, Yan A1 Gibb, James A1 Fidone, Salvatore K1 Neurofisiología AB The carotid body is an arterial chemoreceptor organ responsive to blood levelsof pO2, pCOe and pH 13. The parenchymal tissue of the carotid body is composedmainly of two cell types: the glomus or Type I cells, which are disposed together ingroups or glomeruli, and the sustentacular or Type II cells, which appear as glial-likeelements enclosing the glomeruli in capsular fashion 3,4. The Type I cells, which haveabundant dense-cored vesicles and are known to contain catecholaminesl, 2,11,15,receive a sensory innervation from afferent fibers of the carotid sinus nerve 3. Recentstudies have also shown the presence of reciprocal synapses at these junctions betweenafferent nerve terminals and Type I cells TM. In addition, these cells receive an efferentinnervation from both preganglionic and postganglionic sympathetic fibers whichreach the carotid body from the superior cervical ganglion 18 PB Elsevier SN 0006-8993 YR 1979 FD 1979 LK http://uvadoc.uva.es/handle/10324/7055 UL http://uvadoc.uva.es/handle/10324/7055 LA eng NO Brain Resarch, 172 (1972) 572-576 DS UVaDOC RD 20-abr-2024