RT info:eu-repo/semantics/article
T1 Local sclerotherapy with Polydocanol (Aethoxysklerol®) for the treatment of Epistaxis in Rendu-Osler-Weber or Hereditary Hemorrhagic Telangiectasia (HHT): 15 years of experience*
A1 Morais Pérez, Darío
A1 Millás, Teresa
A1 Zarrabeitia Puente, Roberto
A1 Botella, Luisa M.
A1 Almaraz Gómez, Ana
K1 Cardiovascular, Aparato - Enfermedades
AB Hereditary Haemorrhagic Telangiectasia or Rendu-Osler-Weber syndrome is a rare autosomal dominant vascular disease characterized by mucocutaneous and gastrointestinal telangiectases and localized arteriovenous malformations in lung, brain and liver. Epistaxis, due to rupture of telangiectases of the nasal mucosa, is the most frequent clinical manifestation, leading in many cases to severe impairment of the quality of life in the patients. Though several treatments have been used to reduce epistaxis, none have been completely effective, with the exception of polydocanol (Aethoxysklerol®) in submucosal or subpericondrial injections, which was first presented in 2000 with very good results. After fifteen years using polydocanol in submucosal injections on 45 patients and with nearly 300 injections, we have observed that in 95% of all cases, their nose bleeds improved with respect to frequency and quantity without any important side effects. There was just one case of septal perforation, another with increased septal perforation, and one patient who suffered from dizziness and blurred vision for a few minutes. In this paper the results obtained using this technique over a fifteen-year period will be presented and evaluated.
PB Rhrinology Secretary
SN 0300-0729
YR 2012
FD 2012
LK http://uvadoc.uva.es/handle/10324/8365
UL http://uvadoc.uva.es/handle/10324/8365
LA eng
NO Rhinology. 2012 Mar;50(1):80-86
NO Producción Científica
DS UVaDOC
RD 19-abr-2024