RT info:eu-repo/semantics/article
T1 Accuracy of urea breath test performed immediately after emergency endoscopy in peptic ulcer bleeding
A1 Velayos Jiménez, Benito
A1 Fernández Salazar, Luis Ignacio
A1 Pons Renedo, Fernando
A1 Muñoz Moreno, María Fe
A1 Almaraz Gómez, Ana
A1 Aller de la Fuente, Rocío
A1 Ruiz, Lourdes
A1 Olmo Martínez, María Lourdes del
K1 Test de urea
K1 Endoscopia
AB The aim of this work is to investigate the accuracy of the urea breath test (UBT) performed immediately after emergency endoscopy in peptic ulcer bleeding (PUB).METHODS:Urea breath test was carried out right after emergency endoscopy in patients with PUB. The accuracy of this early UBT was compared to a delayed one after hospital discharge that was considered the gold standard. Clinical and epidemiological factors were analyzed in order to study their influence on the accuracy of the early UBT.RESULTS:Early UBT was collected without any complication and good acceptance from all the 74 patients included. In 53 of the patients (71.6%), a delayed UBT was obtained. Comparing concordance between the two tests we have calculated an accuracy of 83% for the early UBT. Sensibility and specificity were 86.36 and 66%, respectively, with a positive predictive value of 92.68% and negative predictive value of 50% (Kappa index = 0.468; p = 0.0005; CI: 95%). We found no influence of epidemiological factors, clinical presentation, drugs, times to gastroscopy, Forrest classification, endoscopic therapy, hemoglobin, and urea levels over the accuracy of early UBT.CONCLUSIONS:Urea breath test carried out right after emergency endoscopy in PUB is an effective, safe, and easy-to-perform procedure. The accuracy of the test is not modified by clinical or epidemiological factors, ulcer stage, or by the type of therapy applied. However, we have found a low negative predictive value for early UBT, so a delayed test is mandatory for all negative cases.
PB Springer Verlag
SN 0163-2116
YR 2012
FD 2012
LK http://uvadoc.uva.es/handle/10324/8370
UL http://uvadoc.uva.es/handle/10324/8370
LA eng
NO Digestive Diseases Science. 2012 Jul;57(7):1880-1886
NO Producción Científica
DS UVaDOC
RD 27-abr-2024