TY - JOUR AU - Río Lorenzo, Alba del AU - Rojo Ruiz, Jonathan AU - Alonso Alonso, María Teresa AU - García-Sancho Martín, Francisco Javier PY - 2020 SN - 1477-9137 UR - http://uvadoc.uva.es/handle/10324/45019 AB - Sarcopenia, the loss of muscle mass and strength associated with age, has been linked to impairment of the cytosolic Ca2+ peak that triggers muscle contraction, but mechanistic details remain unknown. Here we explore the hypothesis that a reduction in... LA - eng PB - The Company of Biologists KW - Calcium homeostasis KW - Homeostasis del calcio KW - Drosophila melanogaster KW - Endoplasmic reticulum KW - Retículo endoplasmático KW - Sarcopenia KW - Sarcoplasmic reticulum KW - Retículo sarcoplasmático TI - Sarcoplasmic reticulum Ca2+ decreases with age and correlates with the decline in muscle function in Drosophila DO - 10.1242/jcs.240879 ER -