RT info:eu-repo/semantics/article
T1 Detection of Catechol using Mixed Langmuir-Blodgett Films of a Phospholipid and Phthalocyanines as Voltammetric Sensors
A1 Rodríguez Méndez, María Luz
A1 Alessio, Priscila
A1 Pavinato, Felippe J.
A1 Oliveira, Osvaldo N.
A1 Saja Sáez, José Antonio de
A1 Constantino, Carlos José Leopoldo
AB The combination of metallic phthalocyanines (MPcs) and biomolecules has been explored in the literature either as mimetic systems to investigate molecular interactions or as supporting layers to immobilize biomolecules. Here, Langmuir–Blodgett (LB) films containing the phospholipid dimyristoyl phosphatidic acid (DMPA) mixed either with iron phthalocyanine (FePc) or with lutetium bisphthalocyanine (LuPc2) were applied as ITO modified-electrodes in the detection of catechol using cyclic voltammetry. The mixed Langmuir films of FePc + DMPA and LuPc2 + DMPA displayed surface-pressure isotherms with no evidence of molecular-level interactions. The Fourier Transform Infrared (FTIR) spectra of the multilayer LB films confirmed the lack of interaction between the components. The DMPA and the FePc molecules were found to be oriented perpendicularly to the substrate, while LuPc2 molecules were randomly organized. The phospholipid matrix induced a remarkable electrocatalytic effect on the phthalocyanines; as a result the mixed LB films deposited on ITO could be used to detect catechol with detection limits of 4.30 × 10−7 and 3.34 × 10−7 M for FePc + DMPA and LuPc2 + DMPA, respectively. Results from kinetics experiments revealed that ion diffusion dominated the response of the modified electrodes. The sensitivity was comparable to that of other non-enzymatic sensors, which is sufficient to detect catechol in the food industry. The higher stability of the electrochemical response of the LB films and the ability to control the molecular architecture are promising for further studies with incorporation of biomolecules.
SN 0003-2654
YR 2010
FD 2010
LK http://uvadoc.uva.es/handle/10324/30780
UL http://uvadoc.uva.es/handle/10324/30780
LA eng
NO Analyst  vol. 135 p. 2591-2599
NO Producción Científica
DS UVaDOC
RD 29-abr-2024