RT info:eu-repo/semantics/article
T1 Effect of Two Meal Replacement strategies on Cardiovascular Risk Parameters in Advanced Age Patients with Obesity and Osteoarthritis
A1 López Gómez, Juan José
A1 Izaola Jauregui, Olatz
A1 Primo Martín, David
A1 Torres Torres, Beatriz
A1 Gómez Hoyos, Emilia
A1 Ortolá Buigues, Ana
A1 Martín Ferrero, Miguel Ángel
A1 Luis Román, Daniel Antonio de
K1 Obesity
K1 Obesidad
K1 Osteoarthritis
K1 Osteoartritis
K1 Cardiovascular risk
K1 Riesgo cardiovascular
AB Background and aims: Meal replacement diets consist of replacing one or more meals with an artificial nutritional supplement. The objective of this study was to compare the effect of one against two meal replacement strategies on body composition and cardiovascular risk parameters in patients with obesity. Methods: A randomized clinical trial was designed with a modified hypocaloric diet with an artificial nutritional preparation replacing one or two meals for three months in patients with obesity and osteoarthritis pending orthopedic surgery. An anthropometric evaluation and a measurement of the body composition were done with bioelectrical impedance measurement at the beginning and at three months. Results: A total of 112 patients were recruited. Fifty-two patients (46.4%) were randomized to one replacement and 60 patients (53.6%) to two meal replacements. Eighty-one patients (72.3%) were women, and the average age was 61 (11.03) years. The percentage of weight loss at three months was 8.27 (4.79)% (one meal replacement: 7.98 (5.97)%; two meal replacements: 8.50 (3.48)%; p = 0.56). A decrease in fat mass measured by the fat mass index (FMI) was detected (one meal replacement: −2.15 (1.45) kg/m2 vs. two meal replacements: −2.78 (2.55) kg/m2; p > 0.05), and a relative increase in fat-free mass was observed (one meal replacement: +3.57 (4.61)% vs. two meal replacements: +2.14 (4.45)%; p > 0.05). A decrease in HOMA-IR, systolic blood pressure (SBP), and total cholesterol was observed in both groups without differences between them. Conclusions: The substitution strategies of one or two meal replacements were effective in weight loss and fat mass decrease without differences between the two groups. An improvement in lipid parameters, glycemic control, and systolic blood pressure was observed without differences between strategies.
PB MDPI
SN 2072-6643
YR 2020
FD 2020
LK https://uvadoc.uva.es/handle/10324/52368
UL https://uvadoc.uva.es/handle/10324/52368
LA eng
NO Nutrients, 2020, vol. 12, n. 4, 976
NO Producción Científica
DS UVaDOC
RD 20-may-2024