RT info:eu-repo/semantics/article
T1 How prenatal cortisol levels may differentially affect the neurodevelopment of boys and girls
A1 Mariño Narváez, Carolina
A1 Puertas González, José Antonio
A1 Romero González, Borja
A1 González Pérez, Raquel
A1 Peralta Ramírez, María Isabel
K1 cortisol
K1 Neurosciences
K1 Neurodevelopment
K1 Pregnancy
K1 Cortisol
K1 Neurodesarrollo
K1 Embarazo
K1 61 Psicología
AB Background: Prenatal stress could have serious consequences on maternal and fetal health. In this sense, some studies have stated that maternal HCC during pregnancy could contribute to sex-specific effects on infant neurodevelopment, following the Developmental Origins of Health and Disease Hypothesis. Aim: This study aimed to determine whether maternal hair cortisol concentration (HCC) during each trimester of pregnancy and postpartum could predict the neurodevelopmental outcomes of their 12-month-old offspring, with sex-specific differences considered. Study design: longitudinal. Subjects: The study involved 93 pregnant women and their babies. Outcome measure: Hair samples collected during each trimester and postpartum and The Bayley Scales for Infant Development III was used to assess the infants' abilities. Results: The results showed that maternal HCC during the first and second trimesters could predict language and motor abilities. However, when discriminated by sex, only females' cognitive, expressive language, and fine and gross motor skills were predicted by cortisol, not males. Conclusions: These findings support the idea that non-toxic levels of cortisol can positively influence infants' neurodevelopment.
PB Elsevier
SN 0378-3782
YR 2023
FD 2023
LK https://uvadoc.uva.es/handle/10324/62804
UL https://uvadoc.uva.es/handle/10324/62804
LA eng
NO Early Human Development, 2023, vol.187, 105874
NO Producción Científica
DS UVaDOC
RD 14-may-2024