TY - JOUR AU - Matusevičiūtė, Ramona AU - Ignatavičiūtė, Eglė AU - Mickus, Rokas AU - Bordel Velasco, Sergio AU - Skeberdis, Vytenis Arvydas AU - Raškevičius, Vytautas PY - 2023 SN - 2227-9059 UR - https://uvadoc.uva.es/handle/10324/66545 AB - Gap junctions (GJs) made of connexin-43 (Cx43) are necessary for the conduction of electrical impulses in the heart. Modulation of Cx43 GJ activity may be beneficial in the treatment of cardiac arrhythmias and other dysfunctions. The search for novel... LA - eng PB - MDPI KW - Biomedicine, general KW - Biomedicina KW - Molecular biology KW - Cardiology KW - Cardiac surgery KW - Corazón - Enfermedades KW - Gap junctions (Cell biology) KW - Connexins KW - Cx43 KW - Conductance KW - Contundancia KW - Inhibitors KW - Inhibidores KW - Docking KW - Molecular docking KW - Acoplamiento molecular TI - Evaluation of Cx43 gap junction inhibitors using a quantitative structure-activity relationship model DO - 10.3390/biomedicines11071972 ER -