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    Por favor, use este identificador para citar o enlazar este ítem:http://uvadoc.uva.es/handle/10324/13837

    Título
    Rickettsia slovaca Infection: DEBONEL/TIBOLA
    Autor
    Ibarra, V.
    Oteo, J. A.
    Portillo, A.
    Santibáñez, S.
    Blanco, J. R.
    Metola, L
    Eiros Bouza, José MaríaAutoridad UVA Orcid
    Pérez Martínez, L.
    Sanz, M.
    Año del Documento
    2006
    Editorial
    New York Academy of Sciences
    Descripción
    Producción Científica
    Documento Fuente
    Annals of the New York Academy of Sciences, 2006, vol. 1078, n. 1; p. 206-214
    Résumé
    This study describes the epidemiological, clinical, and microbiological characteristics of a new tick-borne disease in Spain—Dermacentor-borne necrosis erythema lymphadenopathy (DEBONEL). The clinical presentations include an eschar at the site of the tick bite, surrounded by an erythema and painful regional lymphadenopathy. The disease appears during the colder months and its vector is Dermacentor marginatus (D. marginatus). From January 1990 to December 2004, 54 patients presented at Hospital of La Rioja with these clinical and epidemiological data. The ratio of females to males was 32/22. The average age was 37 years. In all cases tick bites were located on the upper body (90% on the scalp). The median incubation period was 4.7 days. Signs and symptoms were mild in all cases. Only a small number of patients presented mild and nonspecific abnormalities in a complete blood cell count and mild elevation of erythrocyte sedimentation rates and C-protein reactive and liver enzyme levels. Serological evidence of acute rickettsiosis was observed in 19 patients (61%). In 29% sera tested by polymerase chain reactions (PCRs) were positive. The sequence obtained from a PCR product revealed 98% identity with Rickettsia sp. strains RpA4, DnS14, and DnS28. All ticks removed from patients were PCR-positive. Sequencing showed 8 of them identified as R. slovaca and 2 as Rickettsia sp. strains RpA4, DnS14, and DnS28.
    Materias (normalizadas)
    Garrapatas - Enfermedades
    Revisión por pares
    SI
    DOI
    10.1196/annals.1374.040
    Idioma
    eng
    URI
    http://uvadoc.uva.es/handle/10324/13837
    Derechos
    openAccess
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    • DEP03 - Artículos de revista [102]
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