Por favor, use este identificador para citar o enlazar este ítem:http://uvadoc.uva.es/handle/10324/15241
Título
Predicting cardiac surgery–associated acute kidney injury: The CRATE score
Autor
Año del Documento
2015
Editorial
Elsevier
Descripción
Producción Científica
Documento Fuente
Journal of Critical Care, 2016, 31 (1): 130–138
Zusammenfassung
Purpose: Acute kidney injury (AKI) is a frequent complication after cardiac surgery and is associated with
increased mortality. The aim was to design a nondialytic AKI score in patients with previously normal renal
function undergoing cardiac surgery.
Methods: Data were collected on 909 patients who underwent cardiac surgery with cardiopulmonary bypass between
2012 and 2014. A total of 810 patients fulfilled the inclusion criteria. Patients were classified as having AKI
based on the RIFLE criteria. Postoperative AKI occurred in 137 patients (16.9%). Several parameters were recorded
preoperatively, intraoperatively, and at intensive care unit admission, looking for a univariate andmultivariate associationwith
AKI risk. A second data set of 741 patients, from2 different hospitals,was recorded as a validation cohort.
Results: Four independent risk factors were included in the CRATE score: creatinine (odds ratio [OR], 9.66; 95% confidence
interval [CI], 4.77-19.56; P b .001), EuroSCORE (OR, 1.40; CI, 1.29-1.52; P b .001), lactate (OR, 1.03; CI, 1.01-
1.04; P b .001), and cardiopulmonary bypass time (OR, 1.01; CI, 1.01-1.02; P b .001). The accuracy of the model was
good, with an area under the curve of 0.89 (CI, 0.85-0.92). The CRATE score retained good discrimination in validation
cohort, with an area under the curve of 0.81 (95% CI, 0.78-0.85).
Conclusions: CRATE score is an accurate and easy to calculate risk score that uses affordable andwidely available variables
in the routine care surgical patients.
Materias (normalizadas)
Cardiovascular, Aparato - Cirugía - Complicaciones y secuelas
Enfermedad renal
ISSN
0883-9441
Revisión por pares
SI
Idioma
eng
Derechos
openAccess
Aparece en las colecciones
Dateien zu dieser Ressource
![Attribution-NonCommercial-NoDerivatives 4.0 International](/themes/Mirage2//images/creativecommons/cc-by-nc-nd.png)