Chemokine (C-C Motif) receptor 2 mediates dendritic cell recruitment to the human colon but Is not responsible for differences observed in dendritic cell subsets, phenotype, and function between the proximal and distal colon

Bernardo Ordiz, David; Durant, Lydia; Mann, Elizabeth R.; Bassity, Elizabeth; Montalvillo Álvarez, Enrique; Man, Ripple; Vora, Rakesh; Reddi, Durga; Bayiroglu, Fahri; Fernández Salazar, Luis Ignacio; English, Nicholas R.; Peake, Simon T.C.; Landy, Jon; Lee, Gui H.; Malietzis, George; Siaw, Yi Harn; Murugananthan, Aravinth U.; Hendy, Philip; Sánchez Recio, Eva; Phillips, Robin K.S.; Garrote Adrados, José Antonio; Scott, Paul; Parkhill, Julian; Paulsen, Malte; Hart, Ailsa L.; Al-Hassi, Hafid O.; Arranz Sanz, Eduardo; Walker, Alan W.; Carding, Simon R.; Knight, Stella C.

doi:10.1016/j.jcmgh.2015.08.006

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Título

Chemokine (C-C Motif) receptor 2 mediates dendritic cell recruitment to the human colon but Is not responsible for differences observed in dendritic cell subsets, phenotype, and function between the proximal and distal colon

Año del Documento

2016

Editorial

Elsevier

Descripción

Producción Científica

Documento Fuente

Cellular and Molecular Gastroenterology and Hepatology, 2016, vol. 2, n. 1, pp. 22-39.e5

Zusammenfassung

Most knowledge about gastrointestinal (GI)-tract dendritic cells (DC) relies on murine studies where CD103+ DC specialize in generating immune tolerance with the functionality of CD11b+/− subsets being unclear. Information about human GI-DC is scarce, especially regarding regional specifications. Here, we characterized human DC properties throughout the human colon.

Materias Unesco

3205 Medicina Interna

3205.03 Gastroenterología

Palabras Clave

Células dendríticas

Colon

ISSN

2352-345X

Revisión por pares

DOI

10.1016/j.jcmgh.2015.08.006

Version del Editor