Proliferative role of Kv11 channels in murine arteries

Barrese, Vincenzo; Cidad Velasco, María del Pilar; Yeung, Shuk Y.; López López, José Ramón; McNeish, Alister J.; Ohya, Susumu; Pérez García, María Teresa; Greenwood, Iain A.

doi:10.3389/fphys.2017.00500

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Título

Proliferative role of Kv11 channels in murine arteries

Autor

Barrese, Vincenzo

Cidad Velasco, María del Pilar

Yeung, Shuk Y.

López López, José Ramón

McNeish, Alister J.

Ohya, Susumu

Pérez García, María Teresa

Greenwood, Iain A.

Año del Documento

2017

Editorial

Frontiers

Descripción

Producción Científica

Documento Fuente

Frontiers in Physiology, 2017, vol 8. 10 p.

Resumen

K+ channels encoded by the ether-a-go-go related gene (ERG1 or KCNH2) are important determinants of the cardiac action potential. Expression of both cardiac isoforms (ERG1a and ERG1b) were identified in murine portal vein and distinctive voltage-gated K+ currents were recorded from single myocytes. The aim of the present study was to ascertain the expression and functional impact of ERG channels in murine arteries.

Palabras Clave

Arterial smooth muscle

Músculo liso vascular

Proliferation

Proliferación

ISSN

1664-042X

Revisión por pares

DOI

10.3389/fphys.2017.00500

Patrocinador

British Heart Foundation (projects PG/06/057/20864 and PG/11/93/21943)
Medical Research Council (project MR/K019074/1)
Ministerio de Economía, Industria y Competitividad (grants BFU2013-45867-R and BFU2016-75360)

Version del Editor

https://www.frontiersin.org/articles/10.3389/fphys.2017.00500/full