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    Por favor, use este identificador para citar o enlazar este ítem:http://uvadoc.uva.es/handle/10324/45472

    Título
    Nosocomial vs. community-acquired infective endocarditis in Spain: Location, trends, clinical presentation, etiology, and survival in the 21st Century
    Autor
    Ortega Loubon, Christian Joseph
    Muñoz Moreno, María FeAutoridad UVA Orcid
    Andrés García, Irene
    Álvarez González, Francisco JavierAutoridad UVA Orcid
    Gómez Sánchez, EstherAutoridad UVA
    Bustamante Munguira, JuanAutoridad UVA Orcid
    Lorenzo López, MarioAutoridad UVA
    Tamayo Velasco, ÁlvaroAutoridad UVA Orcid
    Jorge Monjas, PabloAutoridad UVA
    Resino, Salvador
    Tamayo Gómez, EduardoAutoridad UVA
    Heredia Rodríguez, MaríaAutoridad UVA
    Año del Documento
    2019
    Editorial
    MDPI
    Descripción
    Producción Científica
    Documento Fuente
    Journal of Clinical Medicine, 2019, vol. 8, n. 10. 15 p.
    Résumé
    Major changes have occurred in the epidemiology and etiology of infective endocarditis (IE). Nevertheless, the differences between nosocomial infective endocarditis (NIE) and community-acquired infective endocarditis (CIE) have not been addressed in a population-based study. We conducted a retrospective, nationwide, temporal trend study from 1997 to 2014 analyzing the epidemiology, clinical, geographical, meteorological characteristics of patients diagnosed with IE in Spain, to distinguish NIE from CIE. Among 25,952 patients with IE (62.2 ± 18·6 years; 65.9% men), 45.9% had NIE. The incidence of IE increased from 2.83 to 3.73 due to the NIE incidence increment with a decline in CIE. Patients with NIE were older (63.8 years vs. 60.8 years, p < 0·001), presented a higher Charlson index (1.22 vs. 1.03, p < 0.001), a greater history of implanted cardiac devices (8.7% vs. 4.6%, p < 0.001), and higher mortality (31.5% vs. 21.7%, p < 0.001). The most frequent microorganism for both NIE and CIE was Staphylococcus (p < 0.001), and the North reported a higher incidence (p < 0.001). Risk factors of mortality for NIE were age, Charlson index, hemodialysis, shock, heart failure, and stroke. Risk factors for CIE included female sex, renal disease, and cardiac-device carriers. The etiology of IE shifted from community origins to mostly nosocomial-associated infections. Higher morbidity, mortality, and poorer outcomes are associated with NIE.
    Palabras Clave
    Infective endocarditis
    Endocarditis infecciosa
    Mortality
    Mortalidad
    Etiology
    Etiología
    ISSN
    2077-0383
    Revisión por pares
    SI
    DOI
    10.3390/jcm8101755
    Patrocinador
    Junta de Castilla y León (grant VA161G18)
    Version del Editor
    https://www.mdpi.com/2077-0383/8/10/1755
    Propietario de los Derechos
    © 2019 MDPI
    Idioma
    eng
    URI
    http://uvadoc.uva.es/handle/10324/45472
    Tipo de versión
    info:eu-repo/semantics/publishedVersion
    Derechos
    openAccess
    Aparece en las colecciones
    • DEP11 - Artículos de revista [241]
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    Nosocomial-vs.-community.pdf
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    2.684Mo
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    Attribution-NonCommercial-NoDerivatives 4.0 InternacionalExcepté là où spécifié autrement, la license de ce document est décrite en tant que Attribution-NonCommercial-NoDerivatives 4.0 Internacional

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