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    • SCIENTIFIC PRODUCTION
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    • Dpto. Cirugía, Oftalmología, Otorrinolaringología y Fisioterapia
    • DEP11 - Artículos de revista
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    Por favor, use este identificador para citar o enlazar este ítem:http://uvadoc.uva.es/handle/10324/45756

    Título
    Trends in antidepressants use in Spain between 2015 and 2018: Analyses from a population-based registry study with reference to driving
    Autor
    Gutiérrez Abejón, Eduardo
    Herrera Gómez, Francisco Magno
    Criado Espegel, Paloma
    Álvarez González, Francisco JavierAutoridad UVA Orcid
    Año del Documento
    2020
    Editorial
    MDPI
    Descripción
    Producción Científica
    Documento Fuente
    Pharmaceuticals, 2020, vol. 13, n. 4. 14 p.
    Abstract
    Antidepressants are considered driving-impairing medicines (DIM). This is a population-based registry study that shows the trend in the use of antidepressants in Castile and León, Spain, from 2015 to 2018. Data on antidepressant dispensations at pharmacies and the adjusted use of these medicines by the driver population are presented. For the purposes of analysis, population distribution by age and gender has been taken into account, as well as the three Driving Under the Influence of Drugs, alcohol, and medicines (DRUID) categories. Antidepressants were used by 8.56% of the general population and 5.66% of drivers. Antidepressants were used more commonly by females than by males (12.12% vs. 4.87%, χ² = 1325.124, p = 0.001), and users increased as the age increased, even if women who drive used less antidepressants after turning 60 years of age. Chronic use of antidepressants was relevant (8.28%) in the same way as daily use (3.15%). Most of the consumption included SSRIs (4.99%), which are also known as “other antidepressants” (3.71%). Regardless of antidepressants consumed, users took 2.75 ± 1.19 DIMs, which are mainly anxiolytics (58.80%) and opioids (26.43%). Lastly, regarding consumption of antidepressants according to the DRUID classification, category I predominated over categories II and III. Our findings should serve as a starting point for health and traffic authorities to raise awareness of the risk for traffic accidents, especially involving SSRIs.
    Palabras Clave
    Antidepressants
    Antidepresivos
    Driving
    Conducción
    Drug utilization
    Uso de medicamentos
    Traffic accidents
    Accidentes de tráfico
    ISSN
    1424-8247
    Revisión por pares
    SI
    DOI
    10.3390/ph13040061
    Patrocinador
    Instituto de Salud Carlos III (grant RD16/0017/0006)
    Version del Editor
    https://www.mdpi.com/1424-8247/13/4/61
    Propietario de los Derechos
    © 2020 MDPI
    Idioma
    eng
    URI
    http://uvadoc.uva.es/handle/10324/45756
    Tipo de versión
    info:eu-repo/semantics/publishedVersion
    Derechos
    openAccess
    Collections
    • DEP11 - Artículos de revista [109]
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    Attribution-NonCommercial-NoDerivatives 4.0 InternacionalExcept where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivatives 4.0 Internacional

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