• español
  • English
  • français
  • Deutsch
  • português (Brasil)
  • italiano
    • español
    • English
    • français
    • Deutsch
    • português (Brasil)
    • italiano
    • español
    • English
    • français
    • Deutsch
    • português (Brasil)
    • italiano
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Navegar

    Todo o repositórioComunidadesPor data do documentoAutoresAssuntosTítulos

    Minha conta

    Entrar

    Estatística

    Ver as estatísticas de uso

    Compartir

    Ver item 
    •   Página inicial
    • PRODUÇÃO CIENTÍFICA
    • Departamentos
    • Dpto. Cirugía, Oftalmología, Otorrinolaringología y Fisioterapia
    • DEP11 - Artículos de revista
    • Ver item
    •   Página inicial
    • PRODUÇÃO CIENTÍFICA
    • Departamentos
    • Dpto. Cirugía, Oftalmología, Otorrinolaringología y Fisioterapia
    • DEP11 - Artículos de revista
    • Ver item
    • español
    • English
    • français
    • Deutsch
    • português (Brasil)
    • italiano

    Exportar

    RISMendeleyRefworksZotero
    • edm
    • marc
    • xoai
    • qdc
    • ore
    • ese
    • dim
    • uketd_dc
    • oai_dc
    • etdms
    • rdf
    • mods
    • mets
    • didl
    • premis

    Citas

    Por favor, use este identificador para citar o enlazar este ítem:https://uvadoc.uva.es/handle/10324/55861

    Título
    National temporal trend analysis of infective endocarditis among patients infected with HIV in Spain (1997–2014): A retrospective study
    Autor
    Muñoz Moreno, María FeAutoridad UVA Orcid
    Ryan, Pablo
    Álvaro Meca, Alejandro
    Valencia, Jorge
    Tamayo Gómez, EduardoAutoridad UVA
    Resino García, Salvador
    Año del Documento
    2019
    Editorial
    Elsevier
    Descripción
    Producción Científica
    Documento Fuente
    Journal of Clinical Medicine, 2019, vol. 8, n. 8, 1167
    Resumo
    Background: People living with human immunodeficiency virus (HIV) (PLWH) form a vulnerable population for the onset of infective endocarditis (IE). We aimed to analyze the epidemiological trend of IE, as well as its microbiological characteristics, in PLWH during the combined antiretroviral therapy era in Spain. Methods: We performed a retrospective study (1997–2014) in PLWH with data obtained from the Spanish Minimum Basic Data Set. We selected 1800 hospital admissions with an IE diagnosis, which corresponded to 1439 patients. Results: We found significant downward trends in the periods 1997–1999 and 2008–2014 in the rate of hospital admissions with an IE diagnosis (from 21.8 to 3.8 events per 10,000 patients/year; p < 0.001), IE incidence (from 18.2 to 2.9 events per 10,000 patients/year; p < 0.001), and IE mortality (from 23.9 to 5.5 deaths per 100,000 patient-years; p < 0.001). The most frequent microorganisms involved were staphylococci (50%; 42.7% Staphylococcus aureus and 7.3% coagulase-negative staphylococci (CoNS)), followed by streptococci (9.3%), Gram-negative bacilli (8.3%), enterococci (3%), and fungus (1.4%). During the study period, we found a downward trend in the rates of CoNS (p < 0.001) and an upward trends in streptococci (p = 0.001), Gram-negative bacilli (p < 0.001), enterococci (p = 0.003), and fungus (p < 0.001) related to IE, mainly in 2008–2014. The rate of community-acquired IE showed a significant upward trend (p = 0.001), while the rate of health care-associated IE showed a significant downward trend (p < 0.001). Conclusions: The rates of hospital admissions, incidence, and mortality related to IE diagnosis in PLWH in Spain decreased from 1997 to 2014, while other changes in clinical characteristics, mode of acquisition, and pathogens occurred over this time.
    Materias Unesco
    3202 Epidemiología
    Palabras Clave
    AIDS (Disease)
    SIDA (Enfermedad)
    Infective endocarditis
    Endocarditis infecciosa
    Etiology
    Etiología
    ISSN
    2077-0383
    Revisión por pares
    SI
    DOI
    10.3390/jcm8081167
    Patrocinador
    Instituto de Salud Carlos III (grant PI15/01451)
    Junta de Castilla y León (grant 773/A/13)
    Version del Editor
    https://www.mdpi.com/2077-0383/8/8/1167
    Propietario de los Derechos
    © 2019 The Authors
    Idioma
    eng
    URI
    https://uvadoc.uva.es/handle/10324/55861
    Tipo de versión
    info:eu-repo/semantics/publishedVersion
    Derechos
    openAccess
    Aparece en las colecciones
    • DEP11 - Artículos de revista [242]
    Mostrar registro completo
    Arquivos deste item
    Nombre:
    National-temporal-trend-analysis.pdf
    Tamaño:
    1.334Mb
    Formato:
    Adobe PDF
    Thumbnail
    Visualizar/Abrir
    Atribución 4.0 InternacionalExceto quando indicado o contrário, a licença deste item é descrito como Atribución 4.0 Internacional

    Universidad de Valladolid

    Powered by MIT's. DSpace software, Version 5.10