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    Por favor, use este identificador para citar o enlazar este ítem:https://uvadoc.uva.es/handle/10324/59055

    Título
    Long COVID a new derivative in the chaos of SARS-CoV-2 infection: the emergent pandemic?
    Autor
    Fernández Lázaro, DiegoAutoridad UVA
    Sánchez Serrano, Nerea
    Mielgo Ayuso, Juan FranciscoAutoridad UVA Orcid
    García Hernández, Juan Luis
    González Bernal, Jerónimo J.
    Seco Calvo, Jesús
    Año del Documento
    2021
    Editorial
    MDPI
    Descripción
    Producción Científica
    Documento Fuente
    Journal of Clinical Medicine,2021, Vol. 10, Nº. 24, 5799
    Resumen
    Coronavirus disease 2019 (COVID-19) is a multisystem illness caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), which can manifest with a multitude of symptoms in the setting of end-organ damage, though it is predominantly respiratory. However, various symptoms may remain after acute SARS-CoV-2 infection, and this condition is referred to as “Long COVID” (LC). Patients with LC may develop multi-organ symptom complex that remains 4–12 weeks after the acute phase of illness, with symptoms intermittently persisting over time. The main symptoms are fatigue, post-exertional malaise, cognitive dysfunction, and limitation of functional capacity. Pediatric patients developed the main symptoms of LC like those described in adults, although there may be variable presentations of LC in children. The underlying mechanisms of LC are not clearly known, although they may involve pathophysiological changes generated by virus persistence, immunological alterations secondary to virus–host interaction, tissue damage of inflammatory origin and hyperactivation of coagulation. Risk factors for developing LC would be female sex, more than five early symptoms, early dyspnea, previous psychiatric disorders, and alterations in immunological, inflammatory and coagulation parameters. There is currently no specific treatment for LC, but it could include pharmacological treatments to treat symptoms, supplements to restore nutritional, metabolic, and gut flora balance, and functional treatments for the most disabling symptoms. In summary, this study aims to show the scientific community the current knowledge of LC.
    Materias (normalizadas)
    COVID-19 (Disease)
    Symptoms
    Terapia
    Pandemia
    Infección
    Enfermedades infecciosas
    Materias Unesco
    2420 Virología
    Palabras Clave
    Long COVID
    Pathways
    Biomarkers
    ISSN
    2077-0383
    Revisión por pares
    SI
    DOI
    10.3390/jcm10245799
    Patrocinador
    Junta de Castilla y León y Fondo Europeo de Desarrollo Regional (FEDER) - (FONDO-COVID19 n 07.04.467804.74011.0)
    Version del Editor
    https://www.mdpi.com/2077-0383/10/24/5799
    Propietario de los Derechos
    © 2021 The Authors
    Idioma
    eng
    URI
    https://uvadoc.uva.es/handle/10324/59055
    Tipo de versión
    info:eu-repo/semantics/publishedVersion
    Derechos
    openAccess
    Aparece en las colecciones
    • DEP05 - Artículos de revista [198]
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    Nombre:
    Long-COVID-a-New-Derivative-in-the-Chaos-of-SARS-CoV-2-Infection.pdf
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    Atribución 4.0 InternacionalLa licencia del ítem se describe como Atribución 4.0 Internacional

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