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dc.contributor.authorSultana, Arshiya
dc.contributor.authorHeyat, Md Belal Bin
dc.contributor.authorRahman, Khaleequr
dc.contributor.authorKunnavil, Radhika
dc.contributor.authorFazmiya, Mohamed Joonus Aynul
dc.contributor.authorAkhtar, Faijan
dc.contributor.authorSumbul, null
dc.contributor.authorVidal Mazón, Juan Luis
dc.contributor.authorRodríguez, Carmen Lili
dc.contributor.authorTorre Díez, Isabel de la 
dc.date.accessioned2023-07-05T08:21:54Z
dc.date.available2023-07-05T08:21:54Z
dc.date.issued2022
dc.identifier.citationPharmaceuticals, 2022, Vol. 15, Nº. 11, 1371es
dc.identifier.issn1424-8247es
dc.identifier.urihttps://uvadoc.uva.es/handle/10324/60116
dc.descriptionProducción Científicaes
dc.description.abstractHerbal medicine and nutritional supplements are suggested to treat premenstrual somatic and psycho-behavioural symptoms in clinical guidelines; nonetheless, this is at present based on poor-quality trial evidence. Hence, we aimed to design a systematic review and meta-analysis for their effectiveness in alleviating premenstrual symptoms. The published randomized controlled trials (RCTs) were extracted from Google scholar, PubMed, Scopus and PROSPERO databases. The risk of bias in randomized trials was assessed by Cochrane risk-of-bias tool. The main outcome parameters were analysed separately based on the Premenstrual Symptom Screening Tool and PMTS and DRSP scores. Secondary parameters of somatic, psychological, and behavioural subscale symptoms of PSST were also analysed. Data synthesis was performed assuming a random-effects model, and standardized mean difference (SMDs) was analysed using SPSS version 28.0.0 (IBM, Armonk, NY, USA). A total of 754 articles were screened, and 15 RCTs were included (n = 1211 patients). Primary results for participants randomized to an intervention reported reduced PSST (n = 9), PMTS (n = 2), and DSR (n = 4) scores with (SMD = −1.44; 95% CI: −1.72 to −1.17), (SMD = −1.69; 95% CI: −3.80 to 0.42) and (SMD = 2.86; 95% CI: 1.02 to 4.69) verses comparator with substantial heterogeneity. Physical (SMD = −1.61; 95% CI = −2.56 to −0.66), behavioural (SMD = −0.60; 95% CI = −1.55 to 0.35) and mood (SMD = 0.57; 95% CI = −0.96 to 2.11) subscale symptom groupings of PSST displayed similar findings. Fifty-three studies (n = 8) were considered at low risk of bias with high quality. Mild adverse events were reported by four RCTs. Based on the existing evidence, herbal medicine and nutritional supplements may be effective and safe for PMS.es
dc.format.mimetypeapplication/pdfes
dc.language.isoenges
dc.publisherMDPIes
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectDietary supplementses
dc.subjectDietéticaes
dc.subjectWomen - Health and hygienees
dc.subjectMujeres - Sanidad e Higienees
dc.subjectHerbs - Therapeutic usees
dc.subjectMedicinal plantses
dc.subjectMenstrual cyclees
dc.subjectCiclo menstruales
dc.subjectReproductive healthes
dc.subjectSalud reproductivaes
dc.subjectMeta-analysises
dc.subjectEstadística matemáticaes
dc.subjectSoftware measurementes
dc.subjectProgramas y sistemas de programación - Mediciónes
dc.subject.classificationPMSes
dc.subject.classificationSíndrome premenstruales
dc.titleA systematic review and meta-analysis of premenstrual syndrome with special emphasis on herbal medicine and nutritional supplementses
dc.typeinfo:eu-repo/semantics/articlees
dc.rights.holder© 2022 The Authorses
dc.identifier.doi10.3390/ph15111371es
dc.relation.publisherversionhttps://www.mdpi.com/1424-8247/15/11/1371es
dc.identifier.publicationfirstpage1371es
dc.identifier.publicationissue11es
dc.identifier.publicationtitlePharmaceuticalses
dc.identifier.publicationvolume15es
dc.peerreviewedSIes
dc.identifier.essn1424-8247es
dc.rightsAtribución 4.0 Internacional*
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersiones
dc.subject.unesco32 Ciencias Médicases
dc.subject.unesco1209.01 Estadística Analíticaes


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