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    Por favor, use este identificador para citar o enlazar este ítem:https://uvadoc.uva.es/handle/10324/60347

    Título
    6-week supplementation with Tribulus terrestris L. to trained male CrossFit® athletes on muscle, inflammation, and antioxidant biomarkers: A randomized, single-blind, placebo-controlled trial
    Autor
    Fernández Lázaro, DiegoAutoridad UVA
    Seco Calvo, Jesús
    Pascual Fernández, Jorge
    Domínguez Ortega, Carlos
    Valle Soto, Miguel del
    Mielgo Ayuso, Juan FranciscoAutoridad UVA Orcid
    Año del Documento
    2022
    Editorial
    MDPI
    Descripción
    Producción Científica
    Documento Fuente
    International Journal of Environmental Research and Public Health, 2022, Vol. 19, Nº. 23, 16158
    Resumen
    Tribulus terrestris L. (TT) ingredients have anti-inflammatory and antioxidant activities, but their effects on exercise-induced muscle damage (EIMD) in trained athletes are uncertain. The purpose of this single-blind placebo-controlled trial, in accordance with CONSORT guidelines, was to examine the effect of 6 weeks of TT supplementation on muscle metabolism, inflammation biomarkers, and oxidant status. Thirty trained male CrossFit® athletes were randomly assigned to be supplemented with 770 mg/day of TT (intervention group (IG)) or receive a placebo daily (control group (CG)) for 6 weeks. Muscle damage enzymes, inflammation biomarkers, and Total Antioxidant Status (TAS) were assessed at baseline (T1), 21 days after baseline (T2), and after 42 days (T3). Grace, a Workout of the Day, was measured in T1 and T3. Statistical significance (p < 0.05) was found between IG and CG in Lactate Dehydrogenase (LDH), C-reactive protein (CRP), and TAS levels at the end of the follow-up. Furthermore, TAS levels were significantly (p < 0.05) lower at T2 and T3 relative to baseline in the IG, also LDH and CRP increased significantly (p < 0.05) at T2 and T3 relative to baseline in the CG. No significant (p > 0.05) decreases in muscle damage or inflammation biomarkers were observed, although a slight downward trend was observed after 6 weeks for supplemented athletes. TT supplementation could attenuate the CrossFit® training program-induced oxidative stress, muscle damage, and inflammation which could be due to the natural antioxidant and anti-inflammatory properties of TT.
    Materias (normalizadas)
    Herbs - Toxicology
    Herbs - Therapeutic use
    Dietary supplements
    Dietética
    Entrenamiento deportivo
    Athletics
    Atletismo - Entrenamiento
    Muscles - Diseases
    Músculos - Enfermedades
    Inflammation
    Inflamación
    Exercice
    Ejercicio
    Oxidative stress
    Estrés oxidativo
    Pharmacology
    Materias Unesco
    3206 Ciencias de la Nutrición
    3209 Farmacología
    ISSN
    1660-4601
    Revisión por pares
    SI
    DOI
    10.3390/ijerph192316158
    Version del Editor
    https://www.mdpi.com/1660-4601/19/23/16158
    Propietario de los Derechos
    © 2022 The Authors
    Idioma
    eng
    URI
    https://uvadoc.uva.es/handle/10324/60347
    Tipo de versión
    info:eu-repo/semantics/publishedVersion
    Derechos
    openAccess
    Aparece en las colecciones
    • DEP05 - Artículos de revista [198]
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    Nombre:
    6-Week-Supplementation-with-Tribulus-terrestris-L.pdf
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