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    Por favor, use este identificador para citar o enlazar este ítem:https://uvadoc.uva.es/handle/10324/61151

    Título
    Effects of citrulline supplementation on different aerobic exercise performance outcomes: A systematic review and meta-analysis
    Autor
    Viribay, Aitor
    Fernández Lázaro, DiegoAutoridad UVA
    Fernández Landa, Julen
    Castañeda Babarro, Arkaitz
    Sánchez Collado, Pilar
    Mielgo Ayuso, Juan FranciscoAutoridad UVA Orcid
    Año del Documento
    2022
    Editorial
    MDPI
    Descripción
    Producción Científica
    Documento Fuente
    Nutrients, 2022, Vol. 14, Nº. 17, 3479
    Abstract
    Supplementation with Citrulline (Cit) has been shown to have a positive impact on aerobic exercise performance and related outcomes such as lactate, oxygen uptake (VO2) kinetics, and the rate of perceived exertion (RPE), probably due to its relationship to endogenous nitric oxide production. However, current research has shown this to be controversial. The main objective of this systematic review and meta-analysis was to analyze and assess the effects of Cit supplementation on aerobic exercise performance and related outcomes, as well as to show the most suitable doses and timing of ingestion. A structured literature search was carried out by the PRISMA® (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) and PICOS guidelines in the following databases: Pubmed/Medline, Scopus, and Web of Science (WOS). A total of 10 studies were included in the analysis, all of which exclusively compared the effects of Cit supplementation with those of a placebo group on aerobic performance, lactate, VO2, and the RPE. Those articles that used other supplements and measured other outcomes were excluded. The meta-analysis was carried out using Hedges’ g random effects model and pooled standardized mean differences (SMD). The results showed no positive effects of Cit supplementation on aerobic performance (pooled SMD = 0.15; 95% CI (−0.02 to 0.32); I2, 0%; p = 0.08), the RPE (pooled SMD = −0.03; 95% CI (−0.43 to 0.38); I2, 49%; p = 0.9), VO2 kinetics (pooled SMD = 0.01; 95% CI (−0.16 to 0.17); I2, 0%; p = 0.94), and lactate (pooled SMD = 0.25; 95% CI (−0.10 to 0.59); I2, 0%; p = 0.16). In conclusion, Cit supplementation did not prove to have any benefits for aerobic exercise performance and related outcomes. Where chronic protocols seemed to show a positive tendency, more studies in the field are needed to better understand the effects.
    Materias (normalizadas)
    Nutrition
    Sports - Physiological aspects
    Athletes - Nutrition
    Atletas - Nutrición
    Food additives
    Aditivos alimentarios
    Nutrición - Alimentos
    Dietetics
    Nitric oxide
    Oxido nitrico
    Exercise
    Ejercicio físico
    Endurance sports
    Deportes de resistencia
    Meta-analysis
    Materias Unesco
    3104.06 Nutrición
    2411.06 Fisiología del Ejercicio
    Palabras Clave
    Citrulline
    Citrulina
    ISSN
    2072-6643
    Revisión por pares
    SI
    DOI
    10.3390/nu14173479
    Version del Editor
    https://www.mdpi.com/2072-6643/14/17/3479
    Propietario de los Derechos
    © 2022 The Authors
    Idioma
    eng
    URI
    https://uvadoc.uva.es/handle/10324/61151
    Tipo de versión
    info:eu-repo/semantics/publishedVersion
    Derechos
    openAccess
    Aparece en las colecciones
    • DEP05 - Artículos de revista [198]
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    Effects-of-Citrulline-Supplementation.pdf
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    Atribución 4.0 InternacionalLa licencia del ítem se describe como Atribución 4.0 Internacional

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