Oxygen sensing: Physiology and pathophysiology

Abstract

Oxygen is such an essential element for life that multiple mechanisms have evolved to maintain oxygen homeostasis, including those which detect decreases in arterial O2 and generate adaptive responses to hypoxia. In mammals, oxygen sensing mechanisms are found in erythropoietin-producing cells, peripheral chemoreceptor cells (carotid and aortic bodies), pulmonary artery smooth muscle cells, pulmonary neuroepithelial cells, chromaffin cells, and some specific types of neurons. [Texto extraído del artículo de María Asunción Rocher Martín].