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dc.contributor.authorMartín González, Diego
dc.contributor.authorBordel Velasco, Sergio 
dc.contributor.authorSantos Beneit, Fernando
dc.date.accessioned2024-01-09T13:44:14Z
dc.date.available2024-01-09T13:44:14Z
dc.date.issued2023
dc.identifier.citationMicroorganisms, 2023, Vol. 11, Nº. 5, 1109es
dc.identifier.issn2076-2607es
dc.identifier.urihttps://uvadoc.uva.es/handle/10324/64331
dc.descriptionProducción Científicaes
dc.description.abstractIn this study, we describe the characterization of three efficient chicken feather-degrading Streptomyces bacteria isolated from honeybee samples and assess the impact of their co-cultivation on this activity and antistaphylococcal activity. Streptomyces griseoaurantiacus AD2 was the strain showing the highest keratinolytic activity (4000 U × mL−1), followed by Streptomyces albidoflavus AN1 and Streptomyces drozdowiczii AD1, which both generated approximately 3000 U × mL−1. Moreover, a consortium constituted of these three strains was able to use chicken feathers as its sole nutrient source and growth in such conditions led to a significant increase in antibiotic production. S. griseoaurantiacus AD2 was the only strain that exhibited weak antimicrobial activity against Staphylococcus aureus. UPLC analyses revealed that a significant number of peaks detected in the extracts of co-cultures of the three strains were missing in the extracts of individual cultures. In addition, the production of specialized metabolites, such as undecylprodigiosin and manumycin A, was clearly enhanced in co-culture conditions, in agreement with the results of the antimicrobial bioassays against S. aureus. Our results revealed the benefits of co-cultivation of these bacterial species in terms of metabolic wealth and antibiotic production. Our work could thus contribute to the development of novel microbial-based strategies to valorize keratin waste.es
dc.format.mimetypeapplication/pdfes
dc.language.isoenges
dc.publisherMDPIes
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectStreptomyceses
dc.subjectStaphylococcuses
dc.subjectInfecciones por estafilococos - Tratamientoes
dc.subjectAntibioticses
dc.subjectFeatherses
dc.subjectBiofertilizerses
dc.subjectFertilizantes y abonos orgánicoses
dc.subjectMicrobiologyes
dc.subjectCo-culturees
dc.titleCharacterization of the keratinolytic activity of three streptomyces strains and impact of their co-cultivation on this activityes
dc.typeinfo:eu-repo/semantics/articlees
dc.rights.holder© 2023 The authorses
dc.identifier.doi10.3390/microorganisms11051109es
dc.relation.publisherversionhttps://www.mdpi.com/2076-2607/11/5/1109es
dc.identifier.publicationfirstpage1109es
dc.identifier.publicationissue5es
dc.identifier.publicationtitleMicroorganismses
dc.identifier.publicationvolume11es
dc.peerreviewedSIes
dc.description.projectFondo Europeo de Desarrollo Regional (FEDER), (grant TCUE 2021–2023) - (project 067/229111)es
dc.description.projectUnión Europea, H2020-MSCA-IF-2016 - (grant UE-18-VANRESTREP-740080)es
dc.identifier.essn2076-2607es
dc.rightsAtribución 4.0 Internacional*
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersiones
dc.subject.unesco2414.01 Antibióticoses
dc.subject.unesco2414 Microbiologíaes
dc.subject.unesco3308 Ingeniería y Tecnología del Medio Ambientees


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