Relationship between the FRAX index and physical and cognitive functioning in older people

Abstract

ABSTRACT Objective: To assess the relationship between the FRAX index and the Barthel index/MiniMental State Examination in older people. Patients and methods: Observational descriptive study. Demographic data, comorbidity, dependency and cognitive state, and risk of osteoporotic fracture were collected. Results: A total of 375 patients were included (60% female) Patients with a low-risk FRAX for hip fractures had a higher Mini-mental (25, 95% CI¼24–27 vs. 22, 95%¼21 to 23, p¼.0001), a higher Barthel index (88, 95% CI¼84–93 vs 72, 69 to 76, p¼.0001) without differences in the Charlson index. Bivariate analysis showed an inverse association between FRAX and scales but logistic regression showed only female sex (OR 4.4, 95% CI¼2.6–7.6) and the non-dependent Barthel index (OR¼0.104, 95% CI¼0.014–0.792) remained significant and. Barthel index/Minimental constructed a significant model capable of predicting a risk of hip fracture of >3% measured by the FRAX index, with an area under the curve of 0.76 (95% CI¼0.7–0.81). Conclusions: The FRAX index is related to other markers of geriatric assessment and the association between these variables can predict a risk of hip fracture of >3% measured by the FRAX index.