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dc.contributor.authorCobos-Siles, Marta
dc.contributor.authorCubero-Morais, Pablo
dc.contributor.authorArroyo-Jimenez, Irene
dc.contributor.authorRey-Hernandez, Maria
dc.contributor.authorHernandez-Gomez, Laura
dc.contributor.authorVargas-Parra, Derly Judith
dc.contributor.authorGonzalez-Fernandez, Maria
dc.contributor.authorCazorla-Gonzalez, Marina
dc.contributor.authorGabella-Martin, Miriam
dc.contributor.authorRuiz-Albi, Tomas 
dc.contributor.authorBerezo-Garcia, Jose Angel
dc.contributor.authorGarcia-Cruces-Mendez, Jesus Fernando
dc.contributor.authorMiramontes González, José Pablo
dc.contributor.authorCorral Gudino, Luis 
dc.date.accessioned2024-01-25T18:09:27Z
dc.date.available2024-01-25T18:09:27Z
dc.date.issued2020
dc.identifier.citationInternal and Emergency Medicine, September 2020, vol 15, p. 1533-1544es
dc.identifier.issn1828-0447es
dc.identifier.urihttps://uvadoc.uva.es/handle/10324/65042
dc.descriptionProducción Científicaes
dc.description.abstractInfection with SARS-CoV-2 is becoming the leading cause of death in most countries during the 2020 pandemic. The objective of this study is to assess the association between COVID-19 and cause-specific death. The design is retrospective cohort study. We included data from inpatients diagnosed with COVID-19 between March 18 and April 21, 2020, who died during their hospital stay. Demographic, clinical and management data were collected. Causes of death were ascertained by review of medical records. The sample included 128 individuals. The median age was 84 (IQR 75-89), 57% were men. In 109 patients, the death was caused by SARS-CoV-2 infection, whereas in 19 (14.8%, 95 CI 10-22%), the infection acted only as a precipitating factor to decompensate other pathologies. This second group of patients was older (88y vs 82, p < 0.001). In age-adjusted analysis, they had a greater likelihood of heart failure (OR 3.61 95% CI 1.15-11.32), dependency in activities of daily living (OR 12.07 95% CI 1.40-103.86), frailty (OR 8.73 95% CI 1.37-55.46). The presence of X-ray infiltrates was uncommon (OR 0.07, 95% CI 0.02-0.25). A higher percentage of patient deaths from causes unrelated to COVID-19 complications occurred during the two first weeks of the pandemic. Fifteen percent of patients with COVID-19 infection died from decompensation of other pathologies and the cause of death was unrelated to COVID-19 severe complications. Most of these patients had more comorbidities and were frail and elderly. These findings can partially explain the excess mortality in older people.es
dc.format.mimetypeapplication/pdfes
dc.language.isoenges
dc.publisherSpringeres
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses
dc.subject.classificationAge distribution; COVID-19; Cause of death; Frail elderly; Hospital mortality; Risk factoes
dc.titleCause-specific death in hospitalized individuals infected with SARS-CoV-2: more than just acute respiratory failure or thromboembolic eventses
dc.typeinfo:eu-repo/semantics/articlees
dc.identifier.doi10.1007/s11739-020-02485-y.es
dc.relation.publisherversionhttps://link.springer.com/article/10.1007/s11739-020-02485-yes
dc.identifier.publicationfirstpage1533es
dc.identifier.publicationissue8es
dc.identifier.publicationlastpage1544es
dc.identifier.publicationtitleInternal and Emergency Medicinees
dc.identifier.publicationvolume15es
dc.peerreviewedSIes
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersiones
dc.subject.unesco3205 Medicina Internaes
dc.subject.unesco3205.05 Enfermedades Infecciosases


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