This article focuses on the impact that the recent widening of empirical economics has on
the quest for validity in this field. We begin by summarizing the continuous evolution from a
primarily deductive economics to a more empirical one, especially emphasizing the broader
experimental and survey-based evidence. Although these developments pave the way for an
economics with greater empirical support, they also bring into this field the same validity
concerns that mainstream economists naively thought to be avoidable (i. e., concerns with the
external validity of experiments and with “test validity” issues largely addressed in other social
sciences). We show how, ultimately, such developments force economists to confront some serious
challenges and limitations in the quest for validity arising from four ontological peculiarities of
the social domain: 1) the awareness of the inquiry on the part of the subject being studied; 2) the
lack of relevant structural homogeneity between individuals’ shared psychological properties; 3)
actions holistic dependence on the individuals’ complete past; and 4) the variable and holistic
nature of cultural, conventionally mediated forms of interaction. We finally argue that openly
acknowledging these problems would help economists to tone down their scientificity claims
and avoid pseudo-scientific practices like endorsing assumptions refuted by experience.
