Mesenchymal stem cells for regeneration of the ocular surface

Abstract

The integrity of the corneal epithelium is crucial for maintaining corneal transparency and visual function. Corneal damage due to different circumstances such as chemical or thermal burns, eye surgeries,cicatrizing-autoimmune patholo gies, severe dry eye disease (DED), infections, transplant rejections, or congenital disorders can disrupt the integrity of the corneal epithelium. This type of loss is an important cause of visual impairment and blindness that affects millions of people worldwide.