Impact of ventilator-associated pneumonia on mortality and epidemiological features of patients with secondary peritonitis

Heredia-Rodríguez, María; Peláez, María Teresa; Fierro, Inmaculada; Gómez-Sánchez, Esther; Gómez-Pesquera, Estefanía; Lorenzo, Mario; Álvarez González, Francisco Javier; Bustamante Munguira, Juan; Eiros, José María; Bermejo-Martin, Jesús F.; Gómez-Herreras, José I.; Tamayo Gómez, Eduardo

doi:10.1186/s13613-016-0137-5

Por favor, use este identificador para citar o enlazar este ítem:https://uvadoc.uva.es/handle/10324/83232

Título

Impact of ventilator-associated pneumonia on mortality and epidemiological features of patients with secondary peritonitis

Autor

Heredia-Rodríguez, María

Peláez, María Teresa

Fierro, Inmaculada

Gómez-Sánchez, Esther

Gómez-Pesquera, Estefanía

Lorenzo, Mario

Álvarez González, Francisco Javier

Bustamante Munguira, Juan

Eiros, José María

Bermejo-Martin, Jesús F.

Gómez-Herreras, José I.

Tamayo Gómez, Eduardo

Año del Documento

2016

Editorial

Springer Nature

Descripción

Producción Científica

Documento Fuente

Heredia-Rodríguez, M., Peláez, M. T., Fierro, I., Gómez-Sánchez, E., Gómez-Pesquera, E., Lorenzo, M., Álvarez-González, F. J., Bustamante-Munguira, J., Eiros, J. M., Bermejo-Martin, J. F., Gómez-Herreras, J. I., & Tamayo, E. (2016). Impact of ventilator-associated pneumonia on mortality and epidemiological features of patients with secondary peritonitis. Annals of intensive care, 6(1), 34. https://doi.org/10.1186/s13613-016-0137-5

Résumé

Background: Despite the significant impact of nosocomial infections on the morbidity and mortality of patients staying in the intensive care unit (ICU), no study over the past 20 years has focused specifically on VAP following secondary peritonitis. The objective of the present study was to determine in-hospital mortality and epidemiological features attributed to ventilator-associated pneumonia (VAP) following secondary peritonitis. Methods: Prospective observational study involved 418 consecutive patients admitted in the ICU. Univariate and multivariate analyses were performed to identify risk factors associated with mortality and development of VAP. Results: The incidence of VAP following secondary peritonitis was 9.6 %. Risk factors associated with the development of VAP were hospital-acquired peritonitis, requiring >48 h of mechanical ventilation, and SOFA score. The onset of VAP was late in majority of patients. VAP was developed about 16.8 days after the initiation of the peritonitis. Etiological microorganisms responsible for the peritonitis were different than for VAP. The 90-day in-hospital mortality rate was 47.5 % of VAP patients. Independent factors associated with 30- to 90-day in-hospital mortality were VAP and SOFA. Conclusions: In light of the impact on morbidity and mortality in the ICU, more attention should be given to the concurrent features among VAP and secondary peritonitis.

Revisión por pares

DOI

10.1186/s13613-016-0137-5

Patrocinador

This work was supported in part by a grant from the Gerencia de Salud, Consejería de Sanidad, Junta de Castilla y León (GRS 773/A/13) and the Ministry of Health (PI15/01451).