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Título
Prevalence of ocular and oculodermal melanocytosis in Spanish population with uveal melanoma
Autor
Año del Documento
2012
Editorial
Nature Publishing Group
Descripción
Producción Científica
Documento Fuente
Eye . 2012 Jan;26(1):159-156
Resumen
The aim of this study was to determine the prevalence of ocular and oculodermal melanocytosis (ODM) among patients with uveal melanoma (UM) in a Spanish population.
METHODS:
Retrospective review of the medical records of patients with ODM among patients with UM.
RESULTS:
Ten (11 eyes) of 400 patients (2.7%) with UM associated had ODM. The mean age at diagnosis of UM among patients with ODM was 62 years. One patient had bilateral tumours. UM was diagnosed during a routine-examination in two cases. All tumours were medium (7/11) or large (4/11) in size, with a mean maximum base of 13 mm and height of 7 mm. No patient had extraocular extension or metastatic disease at diagnosis. Enucleation was done in five cases and I-125-brachytherapy in six. The mean follow-up was 43 months. One patient died because of metastasis 2 years after enucleation; one patient is currently on treatment of systemic metastasis 11 years after.
CONCLUSIONS:
ODM is more frequent in spanish population with UM than in American population. Despite the risk of UM in ODM, it is often diagnosed late when a conservative treatment is not indicated.
Materias (normalizadas)
Melanoma ocular
ISSN
0950-222X
Revisión por pares
SI
Idioma
eng
Derechos
openAccess
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