2026-04-27T12:51:10Zhttps://uvadoc.uva.es/oai/request

oai:uvadoc.uva.es:10324/214482021-06-24T07:42:24Zcom_10324_1187com_10324_931com_10324_894com_10324_28542com_10324_952col_10324_1408col_10324_28543

Guevara Pulido, James Oswaldo Andrés García, José María Pedrosa Sáez, Rafael 2014 Producción Científica Enantioenriched trisubstituted lactones were obtained in good yields and moderate to very good enantioselectivities in one-pot process, which implies a sequential organocatalyzed Michael addition of ketones to enals, followed by catalytic intramolecular diastereoselective Tishchenko reaction and lactonization. The final lactones were obtained as single diastereoisomers, demonstrating that the mixture of the anti and syn diastereomers epimerized to the syn hydroxy ester during the oxido-reduction step. application/pdf http://uvadoc.uva.es/handle/10324/21448 eng American Chemical Society Catalizadores Química orgánica One-pot Sequential Organocatalytic Michael-Tishchenko-Lactonization Reactions. Synthesis of Enantioenriched 4, 5, 6 -Trisubstituted - Lactones info:eu-repo/semantics/article TEXT UVaDOC. Repositorio Documental de la Universidad de Valladolid Hispana