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<dc:creator>Larriba González, Yolanda</dc:creator>
<dc:creator>Rueda Sabater, María Cristina</dc:creator>
<dc:creator>Fernández Temprano, Miguel Alejandro</dc:creator>
<dc:creator>Peddada, Shyamal</dc:creator>
<dc:date>2016</dc:date>
<dc:description>The study of biological rhythms is receiving a lot of attention in the literature in&#xd;
recent years. At the core of this research lies the methodological problem of how to&#xd;
detect rhythmic signals in measured data. Night and day, or dark and light patterns&#xd;
impact on human health in many different ways. For this reason, researchers are&#xd;
studying the effect of sleep on the circadian clock in human body during various stages&#xd;
of life. Important components of this clock are the circadian genes which have rhythmic&#xd;
expression overtime with phases suitably matching the night and day. Consequently,&#xd;
the identification of rhythmic signals is a problem of considerable interest for biologists.&#xd;
In this work, we develop a novel statistical procedure to detect rhythmic signals in&#xd;
oscillatory systems based on Order Restricted Inference (ORI). This methodology is&#xd;
tested both on simulations and on real data bases. Moreover the obtained results are&#xd;
compared with the most widely extended rhythmicity detection algorithms in literature.</dc:description>
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<dc:title>A new method for detection of rhythmic signals in oscillatory systems</dc:title>
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