2026-04-14T17:27:50Zhttps://uvadoc.uva.es/oai/requestoai:uvadoc.uva.es:10324/291522021-06-24T07:32:02Zcom_10324_28708com_10324_954com_10324_894col_10324_28709
Metallamacrocycle formation through dimerization of metal bioconjugates derived from amino acids and peptides
Álvarez González, Celedonio Manuel
García Rodríguez, Raúl
Miguel San José, Daniel
Producción Científica
Metallamacrocycles of 12, 16, and 22 members are obtained by deprotonation of the carboxylic group of the side chain of iminopyridine complexes derived from the amino acid β-alanine, and the peptides Gly–Gly and Gly–Gly–Gly. Instead of the expected intramolecular attack to give tridentate (N,N,O) ligands, the deprotonated carboxylate attacks in an inter-molecular manner to give dimers in which the ligand acts as a bridge bonded in a κ2(N,N′) chelating fashion to one metal and as κ(O) to the other metal. The formation of the dimers is supported by NMR spectroscopy, mass spectrometry and X-ray crystallography.
2018-03-19
2018-03-19
2016
info:eu-repo/semantics/article
Dalton Transactions 2016, 45 , pp. 963 – 972
1477-9226
http://uvadoc.uva.es/handle/10324/29152
10.1039/C5DT01256B
eng
http://pubs.rsc.org/en/content/articlelanding/2016/dt/c5dt01256b#!divAbstract
info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by-nc-nd/4.0/
Attribution-NonCommercial-NoDerivatives 4.0 International
Royal Society of Chemistry