2026-04-26T20:11:50Zhttps://uvadoc.uva.es/oai/request
oai:uvadoc.uva.es:10324/314432025-03-26T16:41:31Zcom_10324_31661com_10324_952com_10324_894com_10324_23040com_10324_954col_10324_31662col_10324_23041
UVaDOC author Martín, Victor author Gonçalves, Vanessa Santos Silva author Rodríguez Rojo, Soraya author Nunes, Daniela author Fortunato, Elvira author Martins, Rodrigo author Cocero Alonso, María José author Duarte, Catarina M.M. 2018-09-07T08:51:00Z 2018 The Journal of Supercritical Fluids, 2018, vol.131, p. 124–129. http://uvadoc.uva.es/handle/10324/31443 10.1016/j.supflu.2017.09.001 Production of lipid particles loaded with metal nanoparticles by supercritical fluids based processes has been barely studied. In this work, copper nanoparticles were loaded into glyceryl palmitostearate microparticles by PGSS® (Particles from Gas Saturated Solutions). The effect of different variables, temperature (60-80 ºC), copper load (0.2-5%w/w) and water addition (0 – 40%w/w), in particle size and encapsulation efficiency has been studied. The dispersion of metal nanoparticles in the lipid has been determined by SEM-FIB coupled with EDS mapping. In all cases, mean particle size values lower than 70 μm have been obtained, and encapsulation efficiencies around 60% have been achieved. The addition of water has no negative effect in encapsulation efficiency nor in nanoparticles dispersion within the lipid microparticle, being important since nanoparticles are commonly synthetized in aqueous medium. eng Attribution-NonCommercial-NoDerivatives 4.0 International Production of copper loaded lipid microparticles by PGSS® (particles from gas saturated solutions) process info:eu-repo/semantics/article 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URL https://uvadoc.uva.es/bitstream/10324/31443/1/VMartin_copperlipidmicroparticles_repositorio.pdf File MD5 40b1f71faed7b53c1fd0c0b9ff8e0825 1413543 application/pdf VMartin_copperlipidmicroparticles_repositorio.pdf