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oai:uvadoc.uva.es:10324/429362021-06-24T07:44:04Zcom_10324_1186com_10324_931com_10324_894com_10324_28542com_10324_952col_10324_1404col_10324_28543

2020-10-13T18:07:43Z urn:hdl:10324/42936 Deuterium Exchange between Arenes and Deuterated Solvents in the Absence of a Transition Metal: Synthesis of D-Labeled Fluoroarenes Salamanca Verdugo, Vanesa Albéniz Jiménez, Ana Carmen Producción Científica Fluoroarenes can be selectively deuterated by H/D exchange with common deuterated solvents in the presence of a catalytic amount of an alkali metal carbonate or, for the less acidic arenes, stoichiometric quantities of potassium phosphate. This is a sustainable method that does not need transition metal catalysis or the multistep synthesis of a main-group orga- nometallics. This exchange needs to be taken into account when using H/D scrambling as a mechanistic probe in reactions involving fluoroarenes. 2020-10-13T18:07:43Z 2020-10-13T18:07:43Z 2020 info:eu-repo/semantics/article Eur. J. Org. Chem. 2020, 3206–3212 1434-193X http://uvadoc.uva.es/handle/10324/42936 10.1002/ejoc.202000284 3206 22 3212 European Journal of Organic Chemistry 2020 eng info:eu-repo/semantics/openAccess Wiley-VCH