2026-04-27T14:36:43Zhttps://uvadoc.uva.es/oai/request

oai:uvadoc.uva.es:10324/446242021-06-24T07:17:51Zcom_10324_43677com_10324_954com_10324_894col_10324_43678

The FASTK family of proteins : emerging regulators of mitochondrial RNA biology Jourdain, Alexis A. Popow, Johannes Fuente García, Miguel Ángel de la Martinou, Jean-Claude Anderson, Paul Simarro Grande, María Producción Científica The FASTK family proteins have recently emerged as key post-transcriptional regulators of mitochondrial gene expression. FASTK, the founding member and its homologs FASTKD1–5 are architecturally related RNA-binding proteins, each having a different function in the regulation of mitochondrial RNA biology, from mRNA processing and maturation to ribosome assembly and translation. In this review, we outline the structure, evolution and function of these FASTK proteins and discuss the individual role that each has in mitochondrial RNA biology. In addition, we highlight the aspects of FASTK research that still require more attention. 2021-01-07T08:43:51Z 2021-01-07T08:43:51Z 2017 info:eu-repo/semantics/article Nucleic Acids Research, 2017, vol. 45, n. 19. p. 10941-10947 1362-4962 http://uvadoc.uva.es/handle/10324/44624 10.1093/nar/gkx772 eng https://academic.oup.com/nar/article/45/19/10941/4161989 info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by-nc-nd/4.0/ © 2017 Oxford University Press Attribution-NonCommercial-NoDerivatives 4.0 Internacional Oxford University Press SI