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<dc:creator>Alonso Revuelta, María Isabel</dc:creator>
<dc:creator>Gato Casado, Ángel Luis</dc:creator>
<dc:creator>Moro Balbás, José Antonio</dc:creator>
<dc:creator>Martina, P.</dc:creator>
<dc:creator>Barbosa Ayucar, Enrique</dc:creator>
<dc:date>1999</dc:date>
<dc:description>Producción Científica</dc:description>
<dc:description>The expansive force generated by the positive pressure of the neural tube fluid confined inside the brain  vesicles has  been  shown to  be  a key  factor  during the  earliest stages   of  brain  morphogP.nesis and   development  of chick embryos. In a previous study,we demonstrated the existence of  an  intracavity  extracellular matrix rich  in condroitin  sulfate  in  this  species,  which could be  in­ volved in the regulation of the expa nsive process. In this report, scanning electron microscopy and immunohisto­ chemistry show that,after neurulation,a similar extracel­ lular matrix rich in chondroitin sulfate is present inside the  brain vesicles of rat  embryos during early  enlarge­ ment of the  brain anlage. In vitro treatment of  rat embryos-&#xd;
&#xd;
&#xd;
&#xd;
Abbreviations used in this paper&#xd;
 &#xd;
bryos with B-0-xyloside (a chemical compound which</dc:description>
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<dc:identifier>http://uvadoc.uva.es/handle/10324/4631</dc:identifier>
<dc:language>eng</dc:language>
<dc:publisher>Karger</dc:publisher>
<dc:subject>Embriología</dc:subject>
<dc:subject>Cerebro - Enfermedades</dc:subject>
<dc:title>Involvement of sulfated proteoglycans in embryonic brain expansion at earliest stages of development in rat embryos</dc:title>
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