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oai:uvadoc.uva.es:10324/46312025-02-10T12:43:16Zcom_10324_1132com_10324_931com_10324_894col_10324_1205

Alonso Revuelta, María Isabel Gato Casado, Ángel Luis Moro Balbás, José Antonio Martina, P. Barbosa Ayucar, Enrique 2014-05-02T14:44:33Z 2014-05-02T14:44:33Z 1999 Cell Tissues Organs, 1999, vol. 165, p.1-9 http://uvadoc.uva.es/handle/10324/4631 10.1159/000016667 1 165 9 Cell Tissues Organs 165 The expansive force generated by the positive pressure of the neural tube fluid confined inside the brain vesicles has been shown to be a key factor during the earliest stages of brain morphogP.nesis and development of chick embryos. In a previous study,we demonstrated the existence of an intracavity extracellular matrix rich in condroitin sulfate in this species, which could be in­ volved in the regulation of the expa nsive process. In this report, scanning electron microscopy and immunohisto­ chemistry show that,after neurulation,a similar extracel­ lular matrix rich in chondroitin sulfate is present inside the brain vesicles of rat embryos during early enlarge­ ment of the brain anlage. In vitro treatment of rat embryos- Abbreviations used in this paper bryos with B-0-xyloside (a chemical compound which eng info:eu-repo/semantics/openAccess Embriología Cerebro - Enfermedades Involvement of sulfated proteoglycans in embryonic brain expansion at earliest stages of development in rat embryos info:eu-repo/semantics/article