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oai:uvadoc.uva.es:10324/478892025-03-04T09:47:03Zcom_10324_1186com_10324_931com_10324_894col_10324_1404

León Ona, Iker Alonso Alonso, Elena Rita Mata López, Santiago Alonso Hernández, José Luis 2021-08-18T11:43:43Z 2021-08-18T11:43:43Z 2021 Journal of Physical Chemistry Letters, 2021, vol. 12, n. 29. p. 6983–6987 1948-7185 https://uvadoc.uva.es/handle/10324/47889 10.1021/acs.jpclett.1c01743 Producción Científica We have successfully characterized the structure of testosterone, one of the essential steroids, through high-resolution rotational spectroscopy. A single conformer has been detected, and a total of 404 transitions have been fitted, allowing a precise determination of the rotational constants. It allowed us to unravel that the isolated structure of testosterone adopts an extended disposition. The results obtained in this work highlight how using laser ablation techniques in combination with Fourier transform microwave techniques allow the study of large biomolecules or common pharmaceuticals. It is an important step toward studying relevant biomolecules and developing new analytical techniques with unprecedented sensitivity and resolution. Ministerio de Ciencia e Innovación (grants CTQ2016-76393-P; PID2019-111396GBI00 and FJC2018-037320-I) Junta de Castilla y León (grants VA077U16 and VA244P2) Consejo Europeo de Investigación (grant 610256 NANOCOSMOS) application/pdf eng ACS Publications info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/4.0/ © 2021 The Authors Atribución 4.0 Internacional Chemical structure Estructura química Hydroxyls Hidroxilos Molecules Moléculas Testosterone Testosterona Shape of Testosterone info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion https://pubs.acs.org/doi/10.1021/acs.jpclett.1c01743 SI