2026-04-27T21:53:23Zhttps://uvadoc.uva.es/oai/request

oai:uvadoc.uva.es:10324/544822022-10-04T09:12:23Zcom_10324_1185com_10324_931com_10324_894col_10324_1346

Magnesium Status and Ca/Mg Ratios in a Series of Children and Adolescents with Chronic Diseases Escobedo Monge, Marlene Fabiola Barrado Esteban, Enrique Parodi Román, Joaquín Escobedo Monge, María Antonieta Torres Hinojal, María Carmen Marugán de Miguelsanz, José Manuel Producción Científica Magnesium (Mg) is an essential divalent cation involved in various enzymatic reactions that regulate vital biological functions. The main goal was to evaluate Mg status and its association with nutritional indicators in 78 children and adolescents with chronic diseases. We assessed an‐ thropometric, biochemical, diet, body composition, and bone densitometry valuations. Serum Mg and Ca levels were determined using the standardized method and diet calcium (Ca) and Mg con‐ sumption by a prospective 72 h diet survey. Mean serum Ca (9.9 mg/dL), Mg (2.08 mg/dL) dietary Ca (102% DRI: Dietary Reference Intake), and Mg intake (105% DRI) were normal. A total of 45% had hypomagnesemia, 12% had hypermagnesemia, and 26% and 24% had inadequate and high Mg intake, respectively. Only 6% of patients had poor Mg intake and hypomagnesemia, and 54% and 90% of our series had an elevated serum Ca/Mg ratio > 4.70 (mean 4.79) and a low Ca/Mg intake ratio < 1.70 (mean 1.06), respectively. Both Ca/Mg ratios were linked with the risk of developing other chronic conditions such as cardiovascular disease, type 2 diabetes, syndrome metabolic, and even several cancers. Therefore, 79% of children and adolescents with chronic diseases were at ele‐ vated risk of having abnormal Mg status and developing other chronic illnesses. 2022-08-18T10:51:26Z 2022-08-18T10:51:26Z 2022 info:eu-repo/semantics/article Nutrients, 2022, vol. 14, n. 14, 2941 2072-6643 https://uvadoc.uva.es/handle/10324/54482 10.3390/nu14142941 2941 14 Nutrients 14 2072-6643 spa https://www.mdpi.com/2072-6643/14/14/2941 info:eu-repo/semantics/openAccess http://creativecommons.org/publicdomain/zero/1.0/ © 2022 The authors CC0 1.0 Universal MDPI SI