2026-04-14T15:16:41Zhttps://uvadoc.uva.es/oai/request

oai:uvadoc.uva.es:10324/557002025-03-04T09:47:53Zcom_10324_55675com_10324_954com_10324_894col_10324_55676

Aguado Vesperinas, Raúl Sanz Novo, Miguel Mata López, Santiago León Ona, Iker Alonso Hernández, José Luis 2022 Producción Científica In the present work, we report the first rotational study of N-acetylgalactosamine, a cancer-associated sugar derivative, by means of high-resolution rotational spectroscopy. Two different conformers have been conclusively characterized using broadband Fourier transform microwave spectroscopy coupled with a laser ablation vaporization system. Additionally, we performed a comprehensive analysis of the intramolecular interactions that govern these structures, which allowed us to both characterize the existence of intramolecular hydrogen bond networks that drive the intrinsic conformation panorama of N-acetylgalactosamine and further rationalize the biological role of this aminosugar derivative as part of the Tn antigen. application/pdf https://uvadoc.uva.es/handle/10324/55700 eng American Chemical Society Unveiling the shape of N-Acetylgalactosamine: A cancer-associated sugar derivative info:eu-repo/semantics/article TEXT UVaDOC. Repositorio Documental de la Universidad de Valladolid Hispana