2026-04-23T21:09:12Zhttps://uvadoc.uva.es/oai/request

oai:uvadoc.uva.es:10324/589782023-03-20T20:00:28Zcom_10324_1148com_10324_931com_10324_894col_10324_1270

Rosales Martínez, Antonio Enríquez Giraudo, María Lourdes Jaraíz Maldonado, Martín Pozo Morales, Laura Rodríguez García, Ignacio Díaz Ojeda, Emilio 2020 Producción Científica A new concise general methodology for the synthesis of different tetracyclic meroterpenoids is reported: (±)-aureol (1), the key intermediate of this general route. The synthesis of (±)-aureol (1) was achieved in seven steps (28% overall yield) from (±)-albicanol. The key steps of this route include a C–C bond-forming reaction between (±)-albicanal and a lithiated arene unit and a rearrangement involving 1,2-hydride and 1,2-methyl shifts promoted by BF3•Et2O as activator and water as initiator. application/pdf https://uvadoc.uva.es/handle/10324/58978 eng MDPI Natural products - Synthesis Productos naturales Química orgánica - Síntesis A concise route for the synthesis of tetracyclic meroterpenoids: (±)-aureol preparation and mechanistic interpretation info:eu-repo/semantics/article TEXT UVaDOC. Repositorio Documental de la Universidad de Valladolid Hispana